David Augeri
(609) 314-1539

 

Research Services for medicinal chemical, project leader- oriented guidance by David J. Augeri, PhD, former Med Chem Director.

  • Medicinal Chemistry/Drug Discovery Challenges – ALL ASPECTS MTD, NOAEL, PK, Safety Pharmacology, CYP-Induction, PK-PD relationship, Therapeutic Index Determinations
  • ProDrug Selection/Late Stage Structural Changes to Improve PK
  • Synthetic Organic Chemistry Solutions – Route Selection
  • CMC Chemistry and Regulatory Campaigns to Advance Program to Phase 1 – First in Man, 1.0 KG GMP API and coverage of bench/GLP material to complete IND-Enabling studies and Module 2/3, 21 CFR
  • Designed novel chemotypes to follow lead Clinical Compounds. These novel chemotypes were designed from the very same protein/inhibitor complexes as the lead clinical candidate.

Legal Services Provided by DJ Augeri Pharma Consulting for Synthetic/Medicinal Chemistry Consultant and Expert/Testifying Witness:

  • The US and Canadian Federal Courts require lengthy background reports on either the drug or the general drug class to read in preparation for the case. These reports are sometimes written with attorney staff.
  • Preparations/Patent Review for Markman Hearing in Patent Infringement Cases.
  • DJ Augeri provides careful US Patent review of the document describing inventorship of drug/drug class involved.
  • Reviews and reports on any documents submitted for Discovery by opposition.
  • Provides Testimony for Depositions and Cross-Examinations
  • Professional Medical/Pharmaceutical Documents Written as Separate Contract Projects.